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1. Different applications
Hard capsules are made by mixing a certain amount of medicinal material extracts with medicated powder or auxiliary materials into uniform powder or granules, filling them into hollow capsules, or directly filling medicinal powders in hollow capsules.
Soft capsules are a packaging method of capsules, which are commonly used in medicines or health foods. It is a capsule prepared by processing liquid medicine or liquid fruit body medicine and sealing it in a soft capsule.
2. Different roles
Soft capsules encapsulate a certain amount of liquid medicine directly, or dissolve or disperse solid medicine in suitable excipients to make a solution, suspension, emulsion or semi-solid, and seal it in a spherical or oval soft capsule material In the capsule.
Hard capsules are capsules in which medicines or suitable auxiliary materials are added into powders, granules, small tablets, pellets, semi-solid or liquids, etc., using appropriate preparation techniques, and filled in hollow capsules.
3. Different features
The liquid oily substance of the soft capsule can be directly enclosed in the capsule, without the need to use additives such as adsorption and inclusion, and the oily substance content of the soft capsule is as high as 60%-85% (weight), and the content of the inclusion is 50%. the following.
In the production of modern traditional Chinese medicine preparations, hard capsules have been widely used in recent years because of their relatively simple technological process, convenient taking, quick onset, and effective isolation of bad odors.
4. Different application
Hard capsules are dosage forms made by mixing appropriate amount of medicinal material extracts, medicinal material extracts plus medicated powder or auxiliary materials into uniform powder or granules, and filling them into hard capsules. Mainly oral. The hard capsules are neat and beautiful in appearance, easy to swallow, can mask the bad smell of the medicine, disintegrate quickly, and absorb well.
It is suitable for drugs that are sensitive to light, unstable, or unstable when exposed to moisture or heat, or drugs with a peculiar smell, or drugs that need to be released at a fixed time. Drugs for children and drugs that are highly irritating to the gastric mucosa should not be made into capsules.
Soft capsules are dosage forms made by sealing oils or liquid medicines or suspensions that have no dissolving effect on capsule materials such as gelatin. The characteristics are similar to hard capsules. Hard capsules and soft capsules are processed by suitable methods or processed with other medicinal polymer materials to make the shell insoluble in gastric juice, but disintegrate in the intestinal juice to release the active ingredients, and are enteric-coated capsules.
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